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    Researchers found out that participants using this drug to get a year, lost weight within four weeks and have kept the body weight off through the 56 weeks of the study. Contrave is a combination with the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs which can be made up of more than one active ingredient, which can make them more potent and safer.

    Combo-pilling may be the newest fad or even better the newest into the future under scrutiny and so it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills has become popular could be the fact that by right now there are no long term prescription diet pills that have been approved by the FDA aside from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be licensed by the FDA.

    Seizures really are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug could also raise blood pressure level and heartrate, and shouldn't be used in people with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure levels and heartbeat and must not used in patients with uncontrolled high hypertension, as well as by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients to the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.

    From a psychiatric perspective, evidence points too the ordinary neural mechanism for goal-directed behavior continues to be hijacked through the addiction, and malfunctions so that its ordinary functions are exaggerated and fixated on its object. An object creates a stimulus and also the person engages in a "goal-directed behavioral response" that creates a "natural high"(Bostwick & Bucci, 2008).

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