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On September 26, UCLA researcher reported the outcomes of a study, which indicated that Asians who will be struggling with alcoholism will benefit especially from naltrexone, certainly one of three medications authorized by the U.S. Food and Drug Administration (FDA) for your treatment of alcoholism. Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a particular mutation that produces them prone to benefit from naltrexone, in contrast to about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director from the UCLA Addictions Laboratory. The findings are currently available online ( inside journal Neuropsychopharmacology and are published in the upcoming print edition with the journal.
Using two separate drugs to shed pounds can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people that go through it you ought to err to the side of caution and allow FDA do its job and demand some study be done in order that the public is aware of the side effects and dangers of the medications before we take them. Keep in mind that drug companies will be in business to generate income and that they would say almost anything to keep people on his or her medications.
Researchers found that participants investing in this drug to get a year, dropped a few pounds within 4 weeks and have kept the load off through the entire 56 weeks with the study. Contrave is a combination with the drugs naltrexone and bupropion, which seems to reflect a fresh trend of weight-loss drugs that are made up of multiple active ingredient, which may make them more efficient and safer.
Combo-pilling is the newest fad or better yet the newest in the future under scrutiny and therefore it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is now popular may be the fact that by right now there are no long term prescription weight loss supplements that have been approved by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be licensed by the FDA.
Seizures are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug may also raise blood pressure and heart rate, and must not be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.
The FDA also warned that Contrave can raise hypertension and pulse rate and must stop used in patients with uncontrolled high hypertension, and also by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients with a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients for the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking.
"There were no indications of depression or suicidal thoughts in trial participants," said Fujioka.
