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Kerala State Poultry Development Corporation

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  • It was found that naltrexone and bupropion combined, which might be marketed in the future as Contrave, provide better weight loss results than eating and working out alone.

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    Researchers discovered that participants taking this drug for a year, dropped excess weight within 4 weeks and have kept the extra weight off through the 56 weeks from the study. Contrave is really a combination of the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which are made up of many active ingredient, which may make them far better and safer.

    Combo-pilling will be the newest fad or even better the newest in the future under scrutiny and so it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular will be the fact that at the time of right now there aren't long term prescription weight loss supplements that have been authorized by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be authorized by the FDA.

    Seizures really are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug can also raise blood pressure and heartbeat, and mustn't be used in people with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

    The FDA also warned that Contrave can raise blood pressure level and heartrate and must stop used in patients with uncontrolled high blood pressure level, in addition to by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients having a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients on the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking.

    "This is the first drug I'm alert to that targets both appetite and reward centres inside brain," he said.

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