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    Researchers discovered that participants investing in this drug for a year, lost excess weight within a month and have kept the extra weight off through the entire 56 weeks in the study. Contrave is a combination with the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which can be made up of more than one active ingredient, which might make them more efficient and safer.

    Combo-pilling is the newest fad or also the newest ahead under scrutiny and for that reason it is just more publicly known lately, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills has become popular is the fact that as of right now there are not any long term prescription slimming capsules that have been authorized by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be licensed by the FDA.

    Seizures can be a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug also can raise hypertension and heartbeat, and really should not be used in people who have a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug.

    The FDA also warned that Contrave can raise blood pressure and heartbeat and must 't be used in patients with uncontrolled high blood pressure level, in addition to by you are not heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients which has a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients for the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking.

    "This will be the first drug I'm alert to that targets the two appetite and reward centres within the brain," he was quoted saying.

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