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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight loss in addition to a reduced-calorie diet and exercise.
Using two separate drugs to shed weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight-loss and the people that go through it one should err along the side of caution and permit the FDA do its job and demand some study be done in order that the public understands the side effects and risks of the medications before we bring them. Keep in mind that drug companies come in business to make money and that they would say anything to keep people on their medications.
Researchers found out that participants using this drug to get a year, dropped a few pounds within a month and have kept the load off through the entire 56 weeks of the study. Contrave is really a combination with the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs which are made up of several active ingredient, which might make them more efficient and safer.
Combo-pilling could be the newest fad or in addition to this the newest into the future under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular is the fact that at the time of right now there are no long term prescription weightloss pills that have been licensed by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations happen to be rejected or have yet to be authorized by the FDA.
Seizures certainly are a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug also can raise blood pressure and heart rate, and mustn't be used in individuals with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug.
The FDA also warned that Contrave can raise blood pressure level and heart rate and must stop used in patients with uncontrolled high blood pressure, and also by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients having a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients to the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking.
The most common side effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.
