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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment option for chronic weight management in addition to a reduced-calorie diet and exercising.
Using two separate drugs to shed pounds can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight-loss and the people that go through it you need to err on the side of caution and permit the FDA do its job and demand some study be done so that the public recognizes the side effects and dangers of the medications before we bring them. Keep in mind that drug companies come in business to make money and that they would say anything to keep people on his or her medications.
Researchers found out that participants taking this drug to get a year, lost weight within 4 weeks and have kept the body weight off through the 56 weeks with the study. Contrave is often a combination of the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs which are made up of more than one active ingredient, which may make them more efficient and safer.
Combo-pilling will be the newest fad or also the newest ahead under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is becoming popular could be the fact that by right now there are not any long term prescription slimming capsules that have been approved by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be authorized by the FDA.
Seizures really are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug may also raise blood pressure and heartrate, and mustn't be used in people with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug.
The FDA also warned that Contrave can raise blood pressure levels and heart rate and must stop used in patients with uncontrolled high blood pressure levels, in addition to by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients which has a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients towards the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation.
Other people who must avoid using Contrave are patients experiencing bulimia, anorexia nervosa, anyone using opiods, and patients undergoing an 'abrupt discontinuation of alcohol, benzodiazepines, barbiturates and antiepileptic drugs.' Lastly Concave shouldn't be prescribed for women who are pregnant or trying to become pregnant.
