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It was discovered that naltrexone and bupropion combined, which might be marketed down the road as Contrave, provide better weight loss results than diet and exercise alone.
Using two separate drugs to shed pounds can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with weight reduction and the people that go through it you ought to err along the side of caution and allow the FDA do its job and demand some research be done so the public knows the side effects and risks of the medications before we bring them. Keep in mind that drug companies are in business to earn money and that they would say almost anything to keep people on their own medications.
Researchers found that participants investing in this drug to get a year, lost weight within one month and have kept the extra weight off during the entire 56 weeks from the study. Contrave can be a combination from the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which might be made up of many active ingredient, which can make them more effective and safer.
Combo-pilling could be the newest fad or also the newest ahead under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is now popular will be the fact that since right now there are no long term prescription slimming capsules that have been authorized by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be licensed by the FDA.
Seizures are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug may also raise blood pressure level and pulse rate, and shouldn't be used in people with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug.
The FDA also warned that Contrave can raise blood pressure level and heartrate and must stop used in patients with uncontrolled high blood pressure level, and also by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients on the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.
"There were no indications of depression or suicidal thoughts in trial participants," said Fujioka.
