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It was found that naltrexone and bupropion combined, that could be marketed down the road as Contrave, give better weight loss results than diet and exercise alone.
Using two separate drugs to shed weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with fat loss and the individuals who go through it you ought to err to the side of caution and allow the FDA do its job and demand some investigation be done in order that the public knows the side effects and risks of the medications before we bring them. Keep in mind that drug companies are in business to earn money and that they would say everything to keep people on their own medications.
Researchers discovered that participants taking this drug for a year, dropped excess weight within one month and have kept the extra weight off through the 56 weeks in the study. Contrave can be a combination with the drugs naltrexone and bupropion, which usually reflect a fresh trend of weight-loss drugs that are made up of multiple active ingredient, which may make them more efficient and safer.
Combo-pilling could be the newest fad or better yet the newest into the future under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular could be the fact that as of right now there aren't long term prescription weightloss pills that have been licensed by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be licensed by the FDA.
Seizures are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug may also raise blood pressure and heartrate, and mustn't be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug.
The FDA also warned that Contrave can raise blood pressure level and pulse rate and must 't be used in patients with uncontrolled high blood pressure, along with by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients having a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients to the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for smoking cessation.
"This could be the first drug I'm conscious of that targets the appetite and reward centres inside the brain," he said.
